Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
Homologous Recombination02:31

Homologous Recombination

The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...
DNA Packaging00:58

DNA Packaging

Overview
The Replisome03:01

The Replisome

DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

<i>In Situ</i> Imaging of Nanorod Adsorption and Assembly at Liquid Surfaces.

ACS nano·2026
Same author

Revisiting the Conformational Flexibility of DNA 3-Arm Junctions for Nanoconstruction.

Nano letters·2026
Same author

Assembly of Protein-DNA Framework Nanostructures: Structurally Defining Protein-DNA Interfaces With Aptamer.

Angewandte Chemie (International ed. in English)·2026
Same author

Fluorogenic Aptamer Optimization on a Massively Parallel Sequencing Platform.

ACS sensors·2026
Same author

Lifetime-based multiplexed detection of viral RNA using fluorogenic aptamers.

bioRxiv : the preprint server for biology·2026
Same author

Programmable Synthesis of DNA Networks in Giant Vesicles via Rolling Circle Amplification.

Nano letters·2026
Same journal

Linker Engineering toward NIR-II Metal-Organic Framework with Maximal Emission beyond 1000 nm for Inflammatory Bowel Disease Imaging.

Journal of the American Chemical Society·2026
Same journal

Observing Kinetic Selectivity in Anthracene Photodimerization through Selective Quenching by Excited States of Proximate Rare Earth Cations.

Journal of the American Chemical Society·2026
Same journal

Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers.

Journal of the American Chemical Society·2026
Same journal

Large Thermo- and Mechanosalient Actuation via Cooperative Twist Elasticity-Induced Packing Motif Conversion.

Journal of the American Chemical Society·2026
Same journal

Discovery and Biosynthesis of Lanthipeptides Featuring an Azepinoindole Scaffold by Radical <i>S</i>-Adenosylmethionine Enzyme-Catalyzed C-C Bond Formation.

Journal of the American Chemical Society·2026
Same journal

Enantiopurity-Controlled Magnetism in a Two-Dimensional Organic-Inorganic Material.

Journal of the American Chemical Society·2026
関連記事をすべて見る

関連する実験動画

Updated: Jun 20, 2026

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

表面媒介によるDNA自己組み立て

Xuping Sun1, Seung Hyeon Ko, Chuan Zhang

  • 1Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.

Journal of the American Chemical Society
|September 1, 2009
PubMed
まとめ
この要約は機械生成です。

研究者らは,固体表面でのDNAの自己組み立てのための新しい方法を開発しました. この技術はDNAを閉じ込め,2DDNA結晶とナノアレイがミカのような表面に直接成長することを可能にします.

さらに関連する動画

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
08:15

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

Published on: June 26, 2020

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

関連する実験動画

Last Updated: Jun 20, 2026

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
08:15

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

Published on: June 26, 2020

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

科学分野:

  • バイオテクノロジー バイオテクノロジー
  • マテリアルサイエンス 材料科学
  • ナノテクノロジー ナノテクノロジー

背景:

  • DNAの自己組み立ては,ナノスケール構造を作成するための強力な技術です.
  • DNAナノモチーフの柔軟性を制御することは,秩序ある組み立てに不可欠です.
  • 固体表面に直接組み立てることで,製造と特徴付けが簡素化されます.

研究 の 目的:

  • 固体表面媒介DNA自己組み立てのための新しい戦略を報告する.
  • 周期的なDNAナノアレイのインシット成長を実証するために.
  • DNA結晶形成を高めるために,表面封鎖を活用する.

主な方法:

  • 軟弱なDNAと表面の相互作用を利用して閉じ込めます.
  • DNAアセンブリの固体基板としてミカを使用しています.
  • 固体表面にDNAナノ構造を直接組み立てること.

主要な成果:

  • DNA分子が固体表面に閉じ込められる.
  • 閉じ込められたためDNAナノモチーフの柔軟性が低下していることが実証されました.
  • 周期的なDNAナノアレイをミカ表面に直接組み立てました.

結論:

  • 固体表面媒介による閉じ込めは,DNAの自己組み立てのための効果的な戦略です.
  • 表面のインシット組立は,製造プロセスを効率化します.
  • この方法は,ナノテクノロジーや材料科学における様々な応用の可能性を秘めています.