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Updated: Jun 20, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
09:14

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

クツネリド生物合成中のスレオ-およびエリトロベータ-ヒドロキシグルタミン酸のステレオ特異的合成

Matthias Strieker1, Elizabeth M Nolan, Christopher T Walsh

  • 1Department of Chemistry/Biochemistry, Philipps-University, Hans-Meerwein-Strasse, D-35032 Marburg, Germany.

Journal of the American Chemical Society
|September 3, 2009
PubMed
まとめ

研究者らは,2つの酵素,KtzOとKtzPを特定し,固体的にグルタミン酸を水酸化して,ヒドロキシグルタミン酸イソマーを形成する. これらの酵素は,KtzNと共に,抗真菌クツネリドの生成を可能にし,バイオコンビネトリアルエンジニアリングの洞察を提供します.

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