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Updated: Jun 20, 2026

Transmembrane Domain Oligomerization Propensity determined by ToxR Assay
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超膜ヘリコプターの結合を導く力の実験的および計算的評価

Yao Zhang1, Daniel W Kulp, James D Lear

  • 1Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, USA.

Journal of the American Chemical Society
|September 3, 2009
PubMed
まとめ

膜に結合したペプチドの場合は,水溶性タンパク質とは異なり,鍵位置にあるより小さなアミノ酸が安定性を高めます. この研究は,バン・ダー・ウォールス力や静電力によって,残留物の大きさがダイマーの方向性や安定性にどのように影響するかを明らかにしています.

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