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Updated: Jun 20, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

機能化されたサイクロペンタノンの非対称合成は,多触媒二次アミン/N-ヘテロサイクリックカルベンの催化カスケード配列を介して行われます

Stephen P Lathrop1, Tomislav Rovis

  • 1Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.

Journal of the American Chemical Society
|September 8, 2009
PubMed
まとめ

この研究は,機能化されたサイクロペンタノンを合成するための新しい1ポット,非対称な多触媒反応を導入しています. 効率的なプロセスは,容易に入手可能な材料を使用し,二重触媒機構を通じて高いエナチオ選択性を達成します.

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Cycloaddition Reactions: Overview

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[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

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