52歳の女性,障害となる外周神経症: 糖尿病性多神経症のレビュー
1Harvard Medical School, and Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, TCC-810, Boston, MA 02215, USA. srutkove@bidmc.harvard.edu
JAMA
|September 10, 2009
まとめ
糖尿病性多神経症は,激しい痛みとを起こす. 新しい薬物が存在する一方で,古い治療法とアルファリポ酸は,神経疾患の痛みに対して同様の救済を提供することがあります.
科学分野:
- 神経学 神経学とは
- エンドクリノロジー エンドクリノロジー
- 糖尿病学 糖尿病学
背景:
- 糖尿病性多神経症は,糖尿病の一般的な合併症です.
- 神経病的な痛みやなど,著しい罹病率につながります.
- 現在の治療法は,しばしば症状の緩和のみを提供します.
研究 の 目的:
- 糖尿病性多神経症の診断と微分診断をレビューする.
- 糖尿病に関連した神経疾患の痛みに対する現在の症状治療の選択肢について議論する.
- 様々な薬理学的介入の有効性と費用対効果を評価する.
主な方法:
- 糖尿病性多神経症の診断基準に関する文献レビュー.
- 症状性疼痛管理を含む治療戦略の分析.
- 効能と費用の比較評価として,古い薬と新しい薬とサプリメントの比較評価.
主要な成果:
- 糖尿病性多神経症の診断には,差異診断を慎重に検討する必要があります.
- 症状の治療は,神経疾患の痛みとの管理の主要な柱です.
- プレガバリンやドゥロキセチンのような新しい薬は,古い治療法よりも優れた有効性を提供しない可能性があり,より高価です.
- アルファリポ酸は,神経疾患の痛みを緩和する潜在的有効性を示しています.
結論:
- 糖尿病性多神経症の管理は,症状の緩和と,代謝制御を通じて進行を遅らせる可能性に焦点を当てています.
- 費用対効果の高い治療法を優先し,アルファリポ酸を有効な治療法として検討する必要があります.
- 糖尿病性多神経症の新規および確立された治療法に関するさらなる研究が必要である.
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