生まれながらのトキソプラズマ症の予防について何が知られているか?

D Jeannel¹, D Costagliola, G Niel

¹Department of Medical Statistics, Gustave Roussy Institute, Villejuif, France.

Lancet (London, England)

|August 11, 1990

まとめ

フランスフランスフランスフランス

科学分野:

産婦人科と産婦人科を担当しています.
感染症感染症は感染症です.
公衆衛生は公衆衛生である.

背景:

フランスにおける先天性トキソプラズマ症の予防には,妊娠中の急性感染症の診断と治療をスピラマイシンで行うことが含まれる.
プログラムには,血清陰性女性の毎月のフォローアップが含まれています.

研究の目的:

胎児へのトキソプラズモシス感染を予防するスピラマイシンの有効性を評価する.
治療の有効性を評価するために,長期的なフォローアップの実現可能性を評価する.

主な方法:

この研究は,スピラマイシンの有効性に関するランダム化プラセボ対照試験の欠如を強調しています.
必要な6ヶ月の乳児のフォローアップの達成における課題は,母親の感染後のフォローアップの課題が指摘されています.

主要な成果:

生まれながらのトキソプラズマ症を予防するスピラマイシンの有効性は,厳密に評価されていません.
プログラムコストは,妊娠可能な年齢の免疫性のない女性の有病率によって大きく影響されます.

結論:

感染経路と生活習慣に関する健康教育は,妊娠リスクを減らすことができます.
トキソプラズモシス予防のための健康教育戦略のさらなる評価が必要である.

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