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Updated: Jun 20, 2026

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae
10:57

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae

Published on: February 16, 2015

ヒトインスリンを分解する酵素の働き機構

Orazio Amata1, Tiziana Marino, Nino Russo

  • 1Dipartimento di Chimica and Centro di Calcolo ad Alte Prestazioni per Elaborazioni Parallele e Distribuite-Centro d'Eccellenza MURST, Universita' della Calabria, I-87030 Arcavacata di Rende (CS), Italy.

Journal of the American Chemical Society
|September 30, 2009
PubMed
まとめ

インスリン分解酵素 (IDE) はタンパク質分解を効率的に触媒化する. 計算モデリングにより,この反応は低エネルギーバリアを持つ熱外反応であり,酵素活性と一致していることが明らかになった.

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