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Updated: Jun 19, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

CD4+調節性T細胞は,Stat3に依存した方法でTH17反応を制御する

Ashutosh Chaudhry1, Dipayan Rudra, Piper Treuting

  • 1Howard Hughes Medical Institute and Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Science (New York, N.Y.)
|October 3, 2009
PubMed
まとめ

調節性T細胞 (Tregs) は,STAT信号伝達を調節することによって,病原性Tヘルパー17 (Th17) 免疫反応を抑制する. トレグ特異性Stat3の喪失は,この抑制を弱め,致命的な炎症を引き起こす.

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