リボソームタンパク質S6キナーゼ1シグナリングは,哺乳類の寿命を調節する

Colin Selman1, Jennifer M A Tullet, Daniela Wieser

  • 1Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK.

Science (New York, N.Y.)
|October 3, 2009
PubMed
まとめ

マウスのリボソームS6タンパク質キナーゼ1 (S6K1) を削除することで,カロリー制限の効果を模倣し,寿命を延ばし,健康状態を改善しました. これは,S6K1とAMPKの操作が,老化疾患に対する保護を提供することを示唆しています.

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