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Updated: Jun 19, 2026

Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins
11:14

Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins

Published on: January 6, 2017

スプリットタンパク質プロテアゼセンサーの自己抑制型コイル・コイル設計戦略

Sujan S Shekhawat1, Jason R Porter, Akshay Sriprasad

  • 1Department of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, USA.

Journal of the American Chemical Society
|October 7, 2009
PubMed
まとめ

研究者らは,プロテアゼの活動に反応して活性化する,新しい遺伝子でコードされたバイオセンサを開発した. この新しい自己抑制設計は,カスパーゼ-3のようなプロテアゼを検出するための信号を1000倍に増加させます.

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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

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