カナダの2009年のインフルエンザA型 (H1N1) 感染症の重症患者
Anand Kumar1, Ryan Zarychanski, Ruxandra Pinto
1Section of Critical Care Medicine, Health Sciences Centre, JJ 399, 700 William Ave, Winnipeg, MB R3E-0Z3 Canada. akumar61@yahoo.com
JAMA
|October 14, 2009
まとめ
カナダの2009年のインフルエンザA (H1N1) の重症患者は,急速な疾患進行,重度の低酸素症,臓器不全を経験しました. 結果は,長期にわたる機械呼吸と有意な死亡率を含み,集中治療の必要性を強調しました.
科学分野:
- 感染症 感染症は感染症です.
- クリティカルケア・メディシン
- エピデミオロジー エピデミオロジー
背景:
- 2009年のインフルエンザA (H1N1) パンデミックでは,北米で多くの症例が報告されました.
- 重症患者の特徴を理解することは,重度のインフルエンザ感染の管理に不可欠です.
研究 の 目的:
- カナダにおける2009年のインフルエンザA (H1N1) の重症患者の特徴を特定する.
- 死亡率と資源使用率を含む,治療と結果について説明する.
主な方法:
- 2009年インフルエンザA ((H1N1) の確認または可能性のある重症患者の168人を対象とした見通し観察研究.
- カナダの38の成人および小児集中治療室 (ICU) から収集されたデータです.
- プライマリアウトカム:28日および90日間の死亡率;二次アウトカム:機械呼吸器およびICU滞在期間.
主要な成果:
- この研究では,若い成人と子供を含まれており,女性の割合が高く,カナダの先住民も含まれていました.
- 急速な重症性疾患,重度の低酸素血症,頻繁な多系統器官不全を呈した患者.
- 機械呼吸器の使用率 (81.0%) とICUでの長期滞在 (平均12日) が高く,救命療法の頻繁な使用が観察されました.
結論:
- 2009年のインフルエンザA (H1N1) による重篤な病気は急速に発展し,若い個人に感染した.
- 重度の低酸素症,臓器不全,および長期にわたる機械呼吸が一般的であり,集中治療の介入を必要とした.
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