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関連する概念動画

American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...

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関連する実験動画

Updated: Jun 19, 2026

Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model
08:20

Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model

Published on: October 27, 2023

ヒューマン・アフリカン・トリパノソミアシス

Reto Brun1, Johannes Blum, Francois Chappuis

  • 1Swiss Tropical Institute, Basel, Switzerland. reto.brun@unibas.ch

Lancet (London, England)
|October 17, 2009
PubMed
まとめ
この要約は機械生成です。

アフリカのヒトトライパノソミアシス (睡眠病) は,サハラ以南のアフリカで見過ごされている熱帯病です. 緊急のニーズには,より良い診断,より安全な薬,および潜在的な排除のための調整されたベクター制御が含まれます.

さらに関連する動画

Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns)
14:26

Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns)

Published on: April 6, 2019

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis
07:59

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis

Published on: May 18, 2016

関連する実験動画

Last Updated: Jun 19, 2026

Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model
08:20

Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model

Published on: October 27, 2023

Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns)
14:26

Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns)

Published on: April 6, 2019

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis
07:59

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis

Published on: May 18, 2016

科学分野:

  • 軽視された熱帯病
  • 寄生虫学とは,寄生虫学である.
  • アフリカにおける公衆衛生

背景:

  • ヒューマン・アフリカン・トリパノソミアシス (睡眠病) は,サハラ以南のアフリカでツェセ・フライによって伝染する原生虫寄生病である.
  • Trypanosoma brucei gambienseは,主に西アフリカと中央アフリカで,ほぼすべての症例を引き起こす.
  • 病気の流行率は,制御の努力によって変動し,政治的不安定性中に再発することが多い.

研究 の 目的:

  • 睡眠病の診断と治療における課題を強調する.
  • この見捨てられた熱帯病に対する介入の改善の必要性を強調する.
  • 連携した行動を通じて病気の撲滅の可能性を議論する.

主な方法:

  • 睡眠病の流行病学と制御に関する現在の理解のレビュー.
  • 既存の診断・治療戦略の限界を分析する.
  • 効果的なベクトル制御と病気の排除のための要件の評価.

主要な成果:

  • 睡眠病は,年間12,000件未満の症例が報告されている障害と致命的な病気です.
  • 現在の治療法は古く,投与が困難で,重度の副作用が伴う.
  • 効果的な制御と除去戦略には,統合された汎アフリカ的ベクトル制御と強化された国家プログラムが必要です.

結論:

  • 新しい,安全で効果的な診断ツールと薬が非常に必要とされています.
  • パンアフリカ全体で連携したベクトル制御は,病原菌の管理に不可欠です.
  • 国家プログラム,国際機関,研究者の共同努力により,睡眠病の撲滅につながる可能性がある.