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Updated: Jun 19, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

ポリケチドデカルボキシル化鎖の終結に先行してo-スルフォネーションが,生物合成の治療に用いられる

Liangcai Gu1, Bo Wang, Amol Kulkarni

  • 1Life Sciences Institute, Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

Journal of the American Chemical Society
|October 20, 2009
PubMed
まとめ

研究者らは,キュラシンA生物合成における新たなデカルボキシル化鎖終結機構を発見した. このプロセスは,硫酸トランスフェラーゼとチオエステラーゼ酵素を用い,天然製品に希少な末端オレフィンを生成します.

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