高密度脂質タンパク質コレステロールの性別差は,低レベルのアルコール消費者の間で見られます
G Weidner1, S L Connor, M A Chesney
1Department of Psychology, State University of New York, Stony Brook 11794.
Circulation
|January 1, 1991
まとめ
適度なアルコールの摂取は,1日1杯でも,女性では高密度脂質タンパク質コレステロール (HDL-C) が高くなりますが,男性ではそうではありません. これは,女性が男性よりも低い摂取量でアルコールのHDL-Cの恩恵を味わう可能性があることを示唆しています.
科学分野:
- 心血管の健康についてです.
- 栄養科学とは,栄養科学である.
- エピデミオロジー エピデミオロジー
背景:
- 高密度脂質タンパク質コレステロール (HDL-C) は,心血管の健康の重要な指標です.
- 低レベルのアルコール消費とHDL-Cの関係を理解することは,公衆衛生のガイドラインにとって重要です.
研究 の 目的:
- 地域社会に住む男性と女性の低アルコール摂取量 (≤1飲み物/日) と高密度脂質タンパク質コレステロール (HDL-C) レベルとの関連を調べる.
- 低アルコール摂取量とHDL-Cの関係において,性差があるかどうかを判断する.
主な方法:
- 12ヶ月間隔の2つの時間点で収集されたデータを用いて,縦断的な研究設計.
- 自己報告されたアルコール摂取量と,血脂質と脂質タンパク質濃度の臨床評価を用いた.
- コミュニティーで暮らす男性と女性のサンプルから抽出したデータを分析し,アルコール摂取をコントロールした.
主要な成果:
- 男性では,1日1杯以下のアルコールの摂取は,HDL-Cレベルと有意な関連性がないことが示された.
- 女性では,1日1杯未満のアルコールの摂取は,高いHDL-Cレベルと正に関連していた.
- アルコールの摂取量とHDL-Cの間のポジティブな関連性は,低消費レベルでも女性で観察されました.
結論:
- この発見は,HDL-Cレベルに対するアルコールの有益な効果は,男性と比較して女性におけるより低い消費の値で発生する可能性があることを示唆しています.
- 低レベルのアルコールの消費は,性に基づいてHDL-Cに差異的な影響を与える可能性があります.
- アルコールとHDL-Cの性特異的関連の背後にあるメカニズムを明らかにするために,さらなる研究が必要である.
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