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Updated: Jun 19, 2026

Metabolic Pathway Confirmation and Discovery Through 13C-labeling of Proteinogenic Amino Acids
07:26

Metabolic Pathway Confirmation and Discovery Through 13C-labeling of Proteinogenic Amino Acids

Published on: January 26, 2012

超分子システムにおけるIle,Leu,Valメチル相関の割り当て:アスパート酸トランスカルバモイラーゼへの応用

Algirdas Velyvis1, Howard K Schachman, Lewis E Kay

  • 1Department of Biochemistry, University of Toronto, Toronto, ON, Canada M5S 1A8.

Journal of the American Chemical Society
|October 29, 2009
PubMed
まとめ

研究者らは,アスパルテートトランスカルバモイラーゼ (ATCase) のような大きなタンパク質複合体のメチル群を割り当てる方法を開発した. 組み合わせテクニックにより,メチル群の86%が割り当てられ,ATP結合時の構造変化が明らかになった.

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