アジアにおける糖尿病
Ambady Ramachandran1, Ronald Ching Wan Ma, Chamukuttan Snehalatha
1India Diabetes Research Foundation and Dr A Ramachandran's Diabetes Hospitals, Chennai, India. ramachandran@vsnl.com
Lancet (London, England)
|October 31, 2009
まとめ
2型糖尿病はアジア人群で増加しており,若い人群に影響を与え,心血管疾患のリスクを高めています. 予防とケアを改善するために,緊急に国家戦略が必要である.
科学分野:
- エンドクリノロジー エンドクリノロジー
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
背景:
- 2型糖尿病の罹患率は,アジア系住民とアジア系移住者の間で急速に増加しています.
- 糖尿病の発症は,白人集団と比較して,アジア人集団ではより若い年齢で起こります.
- アジア人のより若い発症年齢と高い心血管疾患リスク要因は,生涯の心血管疾患リスクを大幅に高めます.
研究 の 目的:
- アジアの集団における糖尿病の独特の病原遺伝的要因と値を強調する.
- 糖尿病による深刻な経済的負担を強調するためです.
- 国民の意識を高めるための国家戦略,医療基準の改善,初等予防プログラムの提唱.
主な方法:
- この研究は,既存の文献と疫学データのレビューです.
- アジアの集団における流行傾向とリスク要因の分析.
- 経済的影響と医療制度の課題の評価.
主要な成果:
- 独特の病原遺伝因子と糖尿病の発症の低い値がアジア人群で観察されています.
- 糖尿病とその合併症による罹病率と死亡率の増加は,若いアジア人の間で一般的です.
- 糖尿病の経済的負担は,個人レベル,社会レベル,国家レベルにおいてかなり大きい.
結論:
- アジアの集団における2型糖尿病の流行の増加に対処するために,緊急の国家戦略が必要である.
- 公衆の意識の向上,医療の標準化,初等予防プログラムの改善は極めて重要です.
- アジアの集団における糖尿病のユニークな特徴を考慮し,標的を絞った介入が必要である.
関連する概念動画
Diabetes: Symptoms, Diagnosis, and Complications
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Diabetes Mellitus: Overview and Type I Subtype
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type I Diabetes II: Pathophysiology
Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Pathophysiology of Diabetes
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
