ヒトのタンパク質-DNAインタラクトームのプロファイリングは,ERK2がインターフェロン信号伝達の転写抑制体であることを明らかにする

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Updated: Jun 19, 2026

Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle
10:05

Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle

Published on: March 5, 2019

Shaohui Hu1, Zhi Xie, Akishi Onishi

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|November 3, 2009
PubMed
まとめ

研究者はヒトのタンパク質とDNAの相互作用 (PDI) をマッピングし,DNAモチーフとタンパク質の間の何千ものつながりを特定しました. この研究は,非従来のDNA結合タンパク質 (uDBPs) を含む新しい相互作用を明らかにし,遺伝子調節に関する理解を広げています.

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Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization08:57

Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization

Published on: October 6, 2019

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

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