肺炎球菌性肺炎の病原化,治療,予防について
Tom van der Poll1, Steven M Opal
1Centre for Infection and Immunity Amsterdam, Centre for Experimental and Molecular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. t.vanderpoll@amc.uva.nl
Lancet (London, England)
|November 3, 2009
まとめ
Streptococcus pneumoniaeは,世界中で肺炎を引き起こしています. このバクテリアが宿主の防御を回避する方法を理解することで,肺炎球菌感染症と戦うためのワクチンや抗生物質の新たな戦略が明らかになる.
科学分野:
- 微生物学 微生物学とは
- 免疫学 免疫学とは
- 感染症 感染症は感染症です.
背景:
- Streptococcus pneumoniaeは,世界的にコミュニティで発症する肺炎の主な原因である.
- 通常,健康な人の上部呼吸道に侵入します.
- 植民地化は,病原体の増殖と宿主の侵入を含むダイナミックなプロセスです.
研究 の 目的:
- 宿主防御の肺炎球菌逃避の分子メカニズムを探求する.
- 肺炎球菌感染症の制御のための潜在的な治療標的を特定する.
主な方法:
- Streptococcus pneumoniae.e.によって使用される分子メカニズムの分析.
- 植民と侵略の間に宿主-病原体相互作用の調査.
主要な成果:
- 肺炎菌は,宿主の検出システムを回避するために洗練された戦略を採用します.
- これらの回避戦術を理解することで,新しい治療アプローチの洞察が得られます.
結論:
- Streptococcus pneumoniaeを制御するには,多面的なアプローチが必要である.
- これには,様々なワクチンの抗原,抗生物質の組み合わせ,免疫補助療法が含まれます.
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Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
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