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Updated: Jun 18, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

単一のペプチド-MHC複合体は,多様で特定のCD8 T細胞のレパートリーを肯定的に選択します

Baomei Wang1, Tina M Primeau, Nancy Myers

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Science (New York, N.Y.)
|November 7, 2009
PubMed
まとめ

病原体認識のためのT細胞の特異性は,自己メジャーヒストコンパティビリティ複合体 (MHC) 分子に依存しています. この研究では,T細胞発達の過程におけるポジティブ・セレクションが,MHC特異的なレパートリーを作り,成熟したT細胞がペプチド特異性を高いことを確認することが示されています.

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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining06:25

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining

Published on: December 23, 2016

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