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Updated: Jun 18, 2026

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
10:17

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

Published on: January 14, 2020

合成DNAスキャフォールドにペプチドリガンドを組み合わせることで,タンパク質親和反応剤を作成する

Berea A R Williams1, Chris W Diehnelt, Paul Belcher

  • 1Center for BioOptical Nanotechnology, Arizona State University, Tempe, Arizona 85287-5201, USA.

Journal of the American Chemical Society
|November 10, 2009
PubMed
まとめ

研究者らは,小さなペプチドリガンドを組み合わせて合成抗体 (シンボディ) を作る新しい方法を開発した. このアプローチは,動物の免疫を回避し,プロテオーム研究のための高親和性タンパク質結合剤を生成します.

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