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Updated: Jun 18, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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Published on: May 4, 2018

プレペプチド遺伝子の置換とバチルス・セレウスによるin vivo処理によるチオシリン変種の生成

Michael G Acker1, Albert A Bowers, Christopher T Walsh

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|November 17, 2009
PubMed
まとめ

研究者らは前駆体ペプチド遺伝子を改変することによって,新種のチオシリン変種を設計した. この構造-活性関係の探求は,これらの強力な天然製品抗生物質の薬理学的な制限を克服することを目的としています.

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