非対称なClpXヘクサマーの構造は,AAA+タンパク質展開機械のヌクレオチド依存運動を明らかにする

Steven E Glynn1, Andreas Martin, Andrew R Nager

  • 1Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell
|November 17, 2009
PubMed
まとめ

タンパク質を展開する機械であるClpXは,ATPを結合するとき,その環構造に不対称性を示す. この非対称性は,タンパク質処理におけるその機能と,そのATPaseサイクル中の機械的な作業において極めて重要です.

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