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Updated: Jun 18, 2026

Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids
13:05

Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids

Published on: June 28, 2019

IspGはエポキシド基板アナログを (E) -4-ヒドロキシ-3-メチルブート-2-エニルジホスファートに変換する:イソプレノイド生物合成におけるIspG触媒への影響

Rodney L Nyland1, Youli Xiao, Pinghua Liu

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Journal of the American Chemical Society
|November 19, 2009
PubMed
まとめ

研究者らは,提案された中間物質 (2R,3R) -4-ヒドロキシ-3-メチル-2,3-エポキシブタニルジホスファート (Epoxy-HMBPP) を,酵素IspG.のために合成しました. この研究は,Epoxy-HMBPPが基質であることを確認し,イソプレノイド生物合成の理解を深める.

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