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Updated: Jun 18, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
07:08

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

ホメオドメインの乱れた尾は,折りたたみと特定の結合の間のトレードオフを提供し,DNAの認識を容易にする

Agnes Tóth-Petróczy1, Istvan Simon, Monika Fuxreiter

  • 1Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

Journal of the American Chemical Society
|November 19, 2009
PubMed
まとめ

ホメオドメインのタンパク質の乱れたN端尾 (N尾) は,タンパク質を固定し,特定の相互作用を促進することによってDNA結合を強化します. このフライキャストメカニズムは,DNA結合の速度と強度の両方を改善します.

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