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Updated: Jul 24, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

誘導されたNIH/3T3細胞の成長にはRaf-1タンパク質キナーゼが必要である

W Kolch1, G Heidecker, P Lloyd

  • 1Laboratory of Viral Carcinogenesis, NIH/NCI, Frederick Cancer Research and Development Center, Maryland 21702-1201.

Nature
|January 31, 1991
PubMed
まとめ

Raf-1キナーゼは,細胞成長シグナル伝達に不可欠です. Raf-1の機能を阻害すると,増殖と変異を阻害し,成長因子受容体とras腫瘍遺伝子の下流の役割を確認します.

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