RNAi: プロカリオットは行動を起こす.
John van der Oost1, Stan J J Brouns
1Laboratory of Microbiology, Wageningen University, 6703 HB Wageningen, Netherlands. john.vanderoost@wur.nl
Cell
|December 1, 2009
まとめ
CRISPR-Casシステムは,微生物に適応免疫を提供する. Pyrococcus furiosusの新たな変種はDNAではなくRNAを標的とし,これらの防御機構の既知の機能を拡張している.
科学分野:
- 微生物学 微生物学とは
- 分子生物学は分子生物学である.
- 遺伝学 遺伝学とは
背景:
- CRISPR-Casシステムは,プロカリオットの適応免疫メカニズムである.
- これらのシステムは,通常,CRISPR由来RNAを用いた外来DNAを標的にします.
- 以前の研究は,CRISPRに関連した (Cas) タンパク質によるDNAターゲティングに焦点を当てていた.
関連する概念動画
Types of RNA
73.8K
Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
73.8K
Types of RNA
16.2K
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
RNA Performs Diverse...
16.2K
Types of RNA
2.1K
No description available
2.1K
Types of RNA
30.5K
No description available
30.5K
Bacterial RNA Polymerase
33.6K
Unlike eukaryotes, bacteria use a single RNA Polymerase (RNAP) to transcribe all genes. The different subunits of bacterial RNAPhave distinct functions. The multisubunit structure of the bacterial RNAP helps the enzyme to maintain catalytic function, facilitate assembly, interact with DNA and RNA, and self-regulate its activity.
In most genes, the transcription site is a single base present upstream of the coding sequence. Though RNAP is a catalytically efficient enzyme, it does not recognize...
In most genes, the transcription site is a single base present upstream of the coding sequence. Though RNAP is a catalytically efficient enzyme, it does not recognize...
33.6K
Bacterial RNA Polymerase
13.5K
No description available
13.5K


