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Updated: Jun 18, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

RNF12は,X染色体不活性化X染色体不活性化のXエンコードドース依存活性化剤です

Iris Jonkers1, Tahsin Stefan Barakat, Eskeatnaf Mulugeta Achame

  • 1Department of Reproduction and Development, Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands.

Cell
|December 1, 2009
PubMed
まとめ

研究者らは,E3ユビキチンリガゼであるRNF12をX染色体不活性化 (XCI) の主要な活性化剤として特定した. その用量は,胎盤哺乳類のXCI開始に影響を与え,遺伝子用量補償に影響を与えます.

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Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome11:15

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

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