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Updated: Jun 9, 2026

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トール型受容体-2は,ヒトの大動脈硬化症における炎症とマトリックス分解を媒介する

Claudia Monaco1, Scott M Gregan, Tina J Navin

  • 1Kennedy Institute of Rheumatology Division, Imperial College, 65 Aspenlea Rd, London W6 8LH, UK. c.monaco@imperial.ac.uk

Circulation
|December 2, 2009
PubMed
まとめ

Toll型受容体-2 (TLR-2) 信号をブロックすると,ヒト動脈硬化症における炎症とマトリックス退化が著しく減少します. この発見は,動脈硬化症とその合併症に対する潜在的な治療戦略としてTLR-2阻害を示唆しています.

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