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なぜ構造的に異なるサイクルペプチドが,HNK-1炭水化物抗原のグリコミメティックであることができるのか

Anirban Bhunia1, Subramanian Vivekanandan, Thomas Eckert

  • 1Institut für Biochemie und Endokrinologie, Veterinrmedizinische Fakultät, Justus-Liebig-Universität Giessen, Frankfurter Str. 100, 35392 Giessen, Germany.

Journal of the American Chemical Society
|December 5, 2009
PubMed
まとめ

周期性ペプチドは,HNK-1 (ヒトの自然殺人細胞-1) の炭水化物を模倣し,神経細胞の増殖を刺激する. 彼らの構造とラミニン受容体との相互作用は,グリコミメティック薬剤の可能性を理解するために分析されました.

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