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Updated: Jun 18, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
08:12

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

シンコナアルカロイドを用いたケチミンの触媒的エナチオセレクティブ水素フォスフォニル化

Shuichi Nakamura1, Masashi Hayashi, Yuichi Hiramatsu

  • 1Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan. snakamur@nitech.ac.jp

Journal of the American Chemical Society
|December 5, 2009
PubMed
まとめ

チラルのアルファアミノフォスフォネートは,ケチミンの有機触媒的エナチオセレクティブ水素フォスフォニレーションによって合成されます. この方法はシンコナアルカロイドを使用し,低触媒負荷でも,高い選択性を持つ両方のエナンチオマーへのアクセスを可能にします.

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