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Updated: Aug 8, 2026

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI
08:22

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI

Published on: January 30, 2012

C. elegansの基礎膜コラーゲンの変異によって引き起こされる胚死亡率

X D Guo1, J J Johnson, J M Kramer

  • 1Department of Biological Sciences, University of Illinois, Chicago 60680.

Nature
|February 21, 1991
PubMed
まとめ

発達に不可欠な基礎膜の欠陥は,胚の死亡を引き起こす可能性があります. この研究は,C. elegansのα 1(IV) コラーゲン遺伝子 (emb-9) の変異を特定し,基礎膜の整合性を胚の発達と関連付けています.

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Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...