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Updated: Jun 17, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
08:09

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale

Published on: April 19, 2021

NMRリラクゼーション分散による興奮タンパク質状態におけるLeu側鎖構成の決定

D Flemming Hansen1, Philipp Neudecker, Pramodh Vallurupalli

  • 1University of Toronto, Department of Molecular Genetics, 1 King's College Circle, Toronto, M5S 1A8, ON, Canada.

Journal of the American Chemical Society
|December 17, 2009
PubMed
まとめ

この研究では,タンパク質の折り畳み中間物質を分析するためにメチルカール・パーセル・メイブーム・ギル (CPMG) 分散実験を用いた単純な方法が紹介されています. これは,Fyn SH3ドメインの展開状態と中間状態の異なるサイドチェーンロータマー分布を明らかにします.

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