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Updated: Jun 17, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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アルファ-アリロキシアセタルデヒドによる,N-ヘテロサイクリックカルベン誘導のエナチオセレクティブマニッヒ反応

Yasufumi Kawanaka1, Eric M Phillips, Karl A Scheidt

  • 1Department of Chemistry, Center for Molecular Innovation and Drug Discovery, Chemistry of Life Processes Institute, Silverman Hall, Northwestern University, Evanston, Illinois 60208, USA.

Journal of the American Chemical Society
|December 17, 2009
PubMed
まとめ

N-ヘテロサイクリックカルベン (NHCs) は,新しいマニッヒ型反応を触媒化し,エナチオセレクティブのβ-アミノ酸誘導体を生成します. このカルベン触媒のコンセプトは,価値あるアミノ酸ベースの化合物の効率的な合成を提供します.

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