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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Synteny and Evolution02:31

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...
Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles, which...
What is Population Genetics?01:25

What is Population Genetics?

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.While some alleles of a given gene might be observed commonly, other variants...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

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Updated: Jun 17, 2026

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

アジアにおけるヒトの遺伝的多様性のマッピング

, Mahmood Ameen Abdulla, Ikhlak Ahmed

    Science (New York, N.Y.)
    |December 17, 2009
    PubMed
    まとめ

    アジアにおける遺伝的多様性は,言語と地理と強く相関しています. 東南アジアは東アジアの人口の主要な源であり,南北の多様性グラデーションを示しています.

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    Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
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    Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis

    Published on: August 12, 2019

    関連する実験動画

    Last Updated: Jun 17, 2026

    Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
    08:35

    Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

    Published on: July 17, 2021

    Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
    10:08

    Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis

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    科学分野:

    • 人口遺伝学 人口遺伝学
    • ゲノミクスゲノミクスとは
    • アントロポロジー人類学

    背景:

    • アジアの膨大な遺伝的多様性はほとんど理解されていません.
    • 以前の研究では,包括的な地理的サンプリングが欠けていました.

    研究 の 目的:

    • アジアの集団における遺伝的多様性の地理的構造を調査する.
    • 遺伝的祖先,地理,言語的属性との関係を探求する.

    主な方法:

    • オートソーム遺伝的多様性の大規模な調査.
    • アジアの人種集団の広範な地理的サンプル分析.
    • 人口の起源と遺伝子フローを追跡するためのハプロタイプ分析.

    主要な成果:

    • 遺伝的祖先は,言語グループと地理的位置の両方と強く相関しています.
    • ほとんどのアジア人集団は,その民族/言語グループ内で遺伝的関連性を示す.
    • 東アジア (EA) のハプロタイプの90%以上は,東南アジア (SEA) または中央南アジア (CSA) の集団に見られます.
    • 東アジアのハプロタイプ多様性は,南から北へ減少するクリナル構造を示しています.
    • EAハプロタイプの50%はSEAにのみ,5%はCSAにのみ見つかっており,SEAがEA集団の主要な祖先源であることを示唆しています.

    結論:

    • 東南アジアは,東アジアの人々の地理的な源泉として重要な役割を果たしました.
    • アジアにおける遺伝的多様性は,地理と言語の歴史の両方によって構成されています.
    • 遺伝子フローにもかかわらず,独特の遺伝パターンはアジアの多様な人口を反映しています.