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Updated: Jun 17, 2026

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts
09:58

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts

Published on: February 24, 2015

メルドラムの酸由来受容体の実践的な非対称結合アルキニル化:キラルベータ-アルキニル酸へのアクセス

Sheng Cui1, Shawn D Walker, Jacqueline C S Woo

  • 1Department of Chemical Process Research and Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, USA. scui@amgen.com

Journal of the American Chemical Society
|December 22, 2009
PubMed
まとめ

この研究は,シンチョニジンをキラルメディエーターとして使用した非対称結合アルキニレーションの実用的な方法を提示しています. このプロセスは,広範な範囲とスケーラビリティを持つキラルベータ-アルキニル酸を効率的に生成します.

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α-Alkylation of Ketones via Enolate Ions

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