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Updated: Mar 16, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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抗うつ薬の効果とうつ病の重症度:患者レベルのメタ解析

Jay C Fournier1, Robert J DeRubeis, Steven D Hollon

  • 1Department of Psychology, University of Pennsylvania, 3720 Walnut St, Philadelphia, PA 19104, USA. jcf@sas.upenn.edu

JAMA
|January 7, 2010
PubMed
まとめ

抗うつ薬の効用は,うつ病の重度によって異なります. 軽度から中等度のうつ病では,薬はプラセボよりもわずかな利点を提供します. しかし,重度のうつ病では,抗うつ剤はプラセボと比較して実質的な利点を示しています.

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