Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Reason and Intuition01:37

Reason and Intuition

5.9K
The human brain processes information for decision-making using one of two routes: an intuitive system and a rational system (Epstein, 1994; popularized by Kahneman, 2011 as System 1 and System 2, respectively). The intuitive system is quick, impulsive, and operates with minimal effort, relying on emotions or habits to provide cues for what to do next, while the rational system is logical, analytical, deliberate, and methodical. Research in neuropsychology suggests that the...
5.9K
Hindsight Biases01:12

Hindsight Biases

3.5K
Hindsight bias leads you to believe that the event you just experienced was predictable, even though it really wasn’t. In other words, you knew all along that things would turn out the way they did. Can you relate this to the phrase "Hindsight is 20/20" now? 
3.5K
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

9.1K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
9.1K
Accessory Structures of the Skin: Hair and Hair Follicles01:16

Accessory Structures of the Skin: Hair and Hair Follicles

5.2K
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
5.2K
Cognitive Learning01:21

Cognitive Learning

1.6K
Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
1.6K
Introspection01:29

Introspection

443
Introspection, long upheld as a reliable route to self-knowledge, involves examining one's thoughts, emotions, and mental processes. It underpins many psychological practices, from mindfulness meditation to psychotherapy and self-help strategies. However, empirical evidence challenges the accuracy of introspection as a means of understanding oneself.Limitations of Introspective InsightSeminal work by Nisbett and Wilson demonstrated that individuals are frequently unaware of the true causes...
443

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

The molecular basis of force selectivity by PIEZO2.

Nature·2026
Same author

Renal PIEZO2 is an essential regulator of renin.

Cell·2025
Same author

PIEZO channels link mechanical forces to uterine contractions in parturition.

Science (New York, N.Y.)·2025
Same author

A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation.

Cell metabolism·2025
Same author

A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation.

bioRxiv : the preprint server for biology·2024
Same author

Chemical mapping of the surface interactome of PIEZO1 identifies CADM1 as a modulator of channel inactivation.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
関連記事をすべて見る

関連する実験動画

Updated: May 5, 2026

Electrophysiological Measurements from a Moth Olfactory System
06:16

Electrophysiological Measurements from a Moth Olfactory System

Published on: March 29, 2011

13.7K

洞察を欲しがるためかゆみ.

Michael Bandell1, Ardem Patapoutian

  • 1Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.

Cell
|January 13, 2010
PubMed
まとめ
この要約は機械生成です。

Mrgprsとして知られるいくつかのGタンパク質結合受容体は,の信号を伝達する. Liu et al. 劉氏など (2009) は,これらの受容体が,抗マラリア薬のクロロクインによって引き起こされるを媒介することを発見した.

さらに関連する動画

Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals
06:55

Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals

Published on: January 18, 2016

9.1K
Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

12.6K

関連する実験動画

Last Updated: May 5, 2026

Electrophysiological Measurements from a Moth Olfactory System
06:16

Electrophysiological Measurements from a Moth Olfactory System

Published on: March 29, 2011

13.7K
Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals
06:55

Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals

Published on: January 18, 2016

9.1K
Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

12.6K

科学分野:

  • 神経科学は神経科学である.
  • 分子生物学は分子生物学である.
  • 皮膚科 皮膚科について

背景:

  • かゆみの感覚は皮膚の神経末端から発生します.
  • かゆみの正確な分子経路は完全に解明されていません.
  • Gタンパク質結合受容体 (GPCR) は,様々な生理学的プロセスに関与しています.

研究 の 目的:

  • クロロクイン誘発のの原因となる分子メカニズムを調査する.
  • かゆみの感覚を媒介する特定の受容体を特定するために.

主な方法:

  • かゆみの反応を研究するためにマウスモデルを使用した.
  • Mrgprファミリー受容体がを媒介する役割を研究した.

主要な成果:

  • MRgprクラスの受容体の特定のメンバーを特定した.
  • これらのMrgpr受容体がの感覚を媒介することを示した.
  • クロロキンの投与は,これらの受容体の活性化と関連しています.

結論:

  • 特定のMrgpr受容体は,クロロクインが誘発したの主要な媒介者である.
  • 薬剤誘発性の分子基礎についての洞察を提供します.
  • 感覚信号伝達におけるGPCRsの役割を強調しています.