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Updated: Apr 6, 2026

High Efficiency Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes and Characterization by Flow Cytometry
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新しい心臓特異性のヒトトロポミオシンイソフォームの分子および機能的特徴

Sudarsan Rajan1, Ganapathy Jagatheesan, Chehade N Karam

  • 1Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati Medical Center, Cincinnati, OH 45267-0524, USA.

Circulation
|January 13, 2010
PubMed
まとめ

新しいトロポミオシン (TPM) アイソフォームであるTPM1kappaは,ヒトの心不全で増加し,マウスでは拡張性心筋症を引き起こす. この発見は,心疾患におけるTMイソフォームスイッチの結果のメカニズムを提供する.

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