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Updated: Jun 17, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
08:47

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Published on: March 6, 2019

水性エネ型反応によるチロシン生物結合:チロシンのためのクリックのような反応

Hitoshi Ban1, Julia Gavrilyuk, Carlos F Barbas

  • 1The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|January 14, 2010
PubMed
まとめ

科学者たちは,サイクルダイアゾジカルボキシアミドを用いた新しい水性チロシン結合反応を開発した. この多用途な方法は,ペプチドとタンパク質を効率的に改変し,生物結合と抗体開発における新しい応用を可能にします.

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