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Updated: Jun 17, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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タンデムアルリボレーション/ラクトニゼーションによる (+) -キニンシオリドBの総合成

Tim G Elford1, Dennis G Hall

  • 1Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2, Canada.

Journal of the American Chemical Society
|January 14, 2010
PubMed
まとめ

研究者らは,イクセリス・チネンシス (Ixeris chinensis) の天然産物である (+) -チネンシオリドBの第1回エナンチオセレクティブ・トータル合成を達成した. この合成は,新しいタンデム・アリルボレーション/ラクトニゼーションとリング・クロージング・メタテシスを利用し,反応性機能群の課題を克服した.

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