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Updated: Jun 17, 2026

Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on (TRO) Approach
12:12

Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on (TRO) Approach

Published on: March 12, 2017

Rho依存転写終結のアロステリックメカニズム

Vitaly Epshtein1, Dipak Dutta, Joseph Wade

  • 1Department of Biochemistry, New York University School of Medicine, New York, New York 10016, USA.

Nature
|January 16, 2010
PubMed
まとめ

細菌のRho因子は,転写の初期にRNAポリメラーゼと結合する. この結合は,遺伝子発現を制御するために,無活性化と解離を含む2段階の終止プロセスを引き起こす.

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RhoC GTPase Activation Assay09:58

RhoC GTPase Activation Assay

Published on: August 22, 2010

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Bacterial Transcription01:53

Bacterial Transcription

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Transcription Attenuation in Prokaryotes02:42

Transcription Attenuation in Prokaryotes

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There are several different mechanisms used to attenuate transcription. In ribosome mediated...
Transcription in Prokaryotes01:28

Transcription in Prokaryotes

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Transcriptional Regulation: Riboswitches

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Bacterial RNA Polymerase

Unlike eukaryotes, bacteria use a single RNA Polymerase (RNAP) to transcribe all genes. The different subunits of bacterial RNAPhave distinct functions. The multisubunit structure of the bacterial RNAP helps the enzyme to maintain catalytic function, facilitate assembly, interact with DNA and RNA, and self-regulate its activity.
In most genes, the transcription site is a single base present upstream of the coding sequence. Though RNAP is a catalytically efficient enzyme, it does not recognize...