Aire,

Jakub Abramson1, Matthieu Giraud, Christophe Benoist

  • 1Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

Cell
|January 21, 2010
PubMed
まとめ

自己免疫調節タンパク質 (Aire) は,核輸送およびスプライシング装置と相互作用することによって,外周組織自己抗原 (PTAs) を標的にします. この研究では,Aireがタイマスにおける自己抗原発現をどのように誘導するかを説明する主要なタンパク質パートナーを特定しています.

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