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Updated: Jun 16, 2026

Assembly and Purification of Prototype Foamy Virus Intasomes
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レトロウイルスインタソームの組み立てとDNA鎖の移転の阻害

Stephen Hare1, Saumya Shree Gupta, Eugene Valkov

  • 1Division of Medicine, Imperial College London, St-Mary's Campus, Norfolk Place, London W2 1PG, UK.

Nature
|February 2, 2010
PubMed
まとめ

ウイルスのDNAに結合するレトロウイルスインテグラーゼの構造を決定し,DNAを宿主染色体に統合する方法を明らかにしました. この構造は,インテグラーゼ阻害剤がウイルス複合体を無効化することによってどのように作用するかを説明します.

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