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Updated: Jun 16, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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Published on: September 17, 2017

Y145Stopヒトプリオンタンパク質アミロイド繊維の適合性柔軟性は,固体核磁気共振スペクトロスコーピーで探査されました

Jonathan J Helmus1, Krystyna Surewicz, Witold K Surewicz

  • 1Department of Chemistry, The Ohio State University, Columbus, Ohio 43210, USA.

Journal of the American Chemical Society
|February 4, 2010
PubMed
まとめ

人間のプリオンタンパク質 (huPrP23-144) アミロイドのN端領域は柔軟でランダムなコイル状である. 核の残留物は制限された運動を示すが,アミロイド核内のいくつかの遅いダイナミクスは,潜在的な化学交換現象を示唆する.

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