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Updated: Jun 16, 2026

Using the E1A Minigene Tool to Study mRNA Splicing Changes
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Using the E1A Minigene Tool to Study mRNA Splicing Changes

Published on: April 22, 2021

ヒストン修正による代替スプライシングの規制

Reini F Luco1, Qun Pan, Kaoru Tominaga

  • 1National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|February 6, 2010
PubMed
まとめ

ヒストンの改変は,タンパク質の多様性を生み出すために,前メッセンジャーRNA (mRNA) の代替スプライシングを直接制御する. 特定のヒストンのマークは,スプライシングファクターの採用に影響を与え,遺伝子発現のためのクロマチンベースの規制システムを明らかにします.

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