RAFの兄弟たちです
1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Cell
|February 10, 2010
まとめ
標的型分子治療は,がんに対して有望な結果を示していますが,限界があります. ある研究では,あるメラノーマサブタイプに対して有効な治療法が,別のメラノーマサブタイプに害を及ぼす可能性があることがわかりました.
科学分野:
- 腫瘍学 腫瘍学
- 分子生物学は分子生物学である.
- 皮膚科 皮膚科について
背景:
- ターゲットを絞った分子療法によって,がん治療の精度が向上します.
- これらの治療法は,がんの成長を促す特定の分子を抑制することを目的としています.
- 皮膚がんであるメラノーマは,分子プロファイルが異なる様々なサブタイプで構成されています.
さらに関連する動画
関連する概念動画
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02:38The Ras Gene
The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...
Ras is a superfamily...
02:38The Ras Gene
The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...
Ras is a superfamily...
04:49Robbers Cave
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01:14Rab Proteins
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Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...
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01:28Rabies
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