関連する実験動画
左側感染症性内心炎の年齢依存性プロファイル: 3つのセンターでの体験
Javier López1, Ana Revilla, Isidre Vilacosta
1Instituto de Ciencias del Corazón, Hospital Clínico Universitario, Valladolid, Spain. javihouston@yahoo.es
Circulation
|February 10, 2010
まとめ
年齢は感染症性内心炎に大きく影響し,高齢の患者は弁損傷が少ないが,手術による死亡率は高い. この研究では,600件の症例を分析し,この深刻な心臓感染症の年齢関連の違いを理解しました.
科学分野:
- 心臓病学 心臓病学
- 感染症 感染症は感染症です.
- エピデミオロジー エピデミオロジー
背景:
- 感染症性内心炎 (IE) の特徴に対する年齢の影響は十分に理解されていません.
- この研究は,左側IEの年齢特有の特徴を分析するこれまでに最大のシリーズを提示しています.
- 総合的な分析のために,患者は年齢四分位数によって層分化されました.
研究 の 目的:
- 年齢が感染症性心内膜炎の流行学,臨床,微生物学,および予後学的側面にどのように影響するか調査する.
- 左側感染性エンドカルディティスの特徴の年齢関連の変動を分析する.
主な方法:
- 3つの高等教育センターで600件の左側感染性エンドカルディティスエピソードの遡及的分析.
- 年齢四分位に分けて患者の階層化.
- 107の年齢層の変数を比較した.
主要な成果:
- 高齢の患者には,女性性,既発性心疾患,糖尿病,がん,およびエンテロコッシーおよびストレプトコッカスボビスによる感染率が高かった.
- 年齢が若い患者は,バルブ不全,穿孔,Staphylococcus aureus感染症を頻繁に呈した.
- 治療アプローチは様々で,高齢の患者は医療管理のみを受ける可能性が高く,結果が悪化し,手術による死亡率が増加しました.
結論:
- 左側感染症性内心炎の年齢増加は,弁機能障害の減少とより有利な微生物学的プロファイルに関連しています.
- しかし,高齢化は,これらの患者における手術による死亡率の有意な増加と関連しています.
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