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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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巨細胞動脈炎におけるTh17およびTh1T細胞応答

Jiusheng Deng1, Brian R Younge, Richard A Olshen

  • 1Division of Immunology and Rheumatology, Stanford University School of Medicine, 269 W Campus Dr, Stanford, CA 94305, USA.

Circulation
|February 10, 2010
PubMed
まとめ

グルココルチコイドは,巨細胞動脈炎 (GCA) のTh17細胞を抑制するが,Th1細胞は抑制しない. 持続的なTh1応答をターゲットにすることは,慢性血管炎の解決に不可欠であり,T細胞周波数をモニタリングすることで,GCA活動を評価することができます.

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