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Updated: Feb 9, 2026

Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle
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Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle

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双鎖RNA依存型タンパク質キナーゼは,病原体感知とストレスと代謝性ホメオスタシスを結びつける

Takahisa Nakamura1, Masato Furuhashi, Ping Li

  • 1Department of Genetics & Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

Cell
|February 11, 2010
PubMed
まとめ

双鎖RNA依存タンパク質キナーゼ (PKR) は,栄養素感知,ERストレス,炎症を結びつけ,代謝を調節する. 肥満におけるPKRの活性化は代謝機能障害を悪化させ,その欠如は過剰な栄養素から保護する.

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