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Updated: Jun 16, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
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グループIの断片化されたヘモグロビンのNO酸化の原子模擬シミュレーション

Sabyashachi Mishra1, Markus Meuwly

  • 1Department of Chemistry, University of Basel, Basel, Switzerland.

Journal of the American Chemical Society
|February 12, 2010
PubMed
まとめ

切断されたヘモグロビン (trHbN) による酸化窒素 (NO) の解毒には,NOの酸化酸素化が含まれます. シミュレーションにより,リガンドの再編成を含む好ましい経路が明らかになり,Tyr33やGln58のような特定の残留物は,この反応を促進するために重要である.

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